Pravadoline CAS 92623-83-1

1. Pravadoline feem ntau yog siv los ua cov cuab yeej tshawb fawb thiab cov tshuaj siv tshuaj siv tshuaj, tshwj xeeb tshaj yog thawj zaug pom cov aminoalkylindole cannabinoid receptor agonist, uas coj mus rau kev txhim kho cov kev tshawb fawb dav dav xws li WIN 55, 212-2 .
2. Pravadoline CAS 92623-83-1 ua haujlwm raws li cyclooxygenase (COX) inhibitor, inhibiting prostaglandin synthesis hauv nas hlwb nrog IC50 ntawm 4.9 µM, thiab qhia txog kev ua haujlwm antinociceptive hauv ntau hom nas mob.
3. Pravadoline nthuav tawm ob lub tswv yim ntawm kev ua, ua raws li ob qho tib si COX inhibitor thiab cannabinoid receptor agonist, nrog rau nws cov teebmeem analgesic tshwm sim ntawm koob tshuaj kaum npaug qis dua nws cov tshuaj tiv thaiv - mob thiab tsis raug thaiv los ntawm opioid antagonists xws li naloxone .
4. Cov kws tshawb fawb Pravadoline CAS 92623-83-1 siv cov khoom no los kawm cov tshuaj cannabinoid receptor pharmacology, tshwj xeeb tshaj yog CB1 thiab CB2 receptor kev sib cuam tshuam, thiab tshawb xyuas cov qauv aminoalkylindole-kev sib raug zoo hauv cov ntaub so ntswg cais nrog rau cov guinea npua ileum thiab nas vas deferens .

1. Pravadoline yuav tsum tau muab cia rau hauv lub thawv kaw nruj nreem kaw hauv qhov txias, qhuav, thiab zoo- qhov chaw muaj cua, tiv thaiv lub teeb thiab cua sov, nrog kev pom zoo cia ntawm -20℃rau kev ruaj ntseg mus ntev txog 3 xyoos lossis ntawm 4℃mus txog 2 xyoos.
2. Pravadoline CAS 92623-83-1 muaj cov tshuaj muaj tshuaj lom thiab raug cais nrog cov lus muaj kev phom sij xws li R28 (muaj tshuaj lom heev yog tias nqos), R38 ( khaus tawv nqaij), R41 (kev pheej hmoo ntawm qhov muag puas tsuaj loj), thiab muaj peev xwm ua rau muaj kev pheej hmoo ntawm fertility thiab tsim kev puas tsuaj rau cov menyuam hauv plab, 6 R3
3. Cov neeg ua haujlwm yuav tsum hnav cov tshuaj lom neeg- cov hnab looj tes tiv thaiv roj hmab, NIOSH/MSHA- pom zoo ua pa ua pa, tsom iav tiv thaiv tshuaj lom neeg, thiab cov khaub ncaws tiv thaiv tsis zoo thaum tuav pravadoline, zam kev nqus cov plua plav thiab tiv thaiv daim tawv nqaij, qhov muag, thiab khaub ncaws.
4. Khaws kom deb ntawm cov ntaub ntawv tsis sib xws xws li cov tshuaj muaj zog oxidizing, muaj zog acids, thiab muaj zog alkalis, thiab rau kev daws teeb meem, npaj aliquots hauv cov vials kaw nruj nreem thiab siv tsis pub dhau 1 lub hlis ntawm -20℃lossis 6 lub hlis ntawm -80 degree.

1. Cais qhov chaw nchuav, ua kom muaj cua txaus, thiab zam cov plua plav tawm thaum pravadoline raug tso tawm, hnav cov khoom tiv thaiv tus kheej nrog rau tus kheej -cov cuab yeej ua pa, tshuaj lom neeg- hnab looj tes tiv thaiv, tsom iav, thiab khaub ncaws tiv thaiv.
2. Sau Pravadoline CAS 92623-83-1 los ntawm kev cheb lossis nqus tsev yam tsis tsim cov plua plav siv cov khoom pov thawj-cov ntaub ntawv pov thawj, lossis nqus cov kev daws teeb meem nrog cov hmoov ua kua nplaum zoo xws li diatomite lossis universal binders, thiab muab tso rau hauv cov thawv kaw tsim nyog rau kev pov tseg.
3. Tsis txhob tsim cov plua plav plua plav thaum lub sij hawm ntxuav kom tsis txhob ua pa tawm, decontaminate qhov chaw thiab cov khoom siv los ntawm kev txhuam nrog cawv, thiab tiv thaiv cov khoom los ntawm kev nkag mus rau hauv cov dej los yog cov dej hauv chav dej.
4. Muab pov tseg Pravadoline CAS 92623-83-1 cov ntaub ntawv raws li lub teb chaws, tsoom fwv teb chaws, xeev, thiab cov kev cai hauv cheeb tsam, vim hais tias cov khoom no raug suav hais tias tsis muaj kev phom sij rau kev thauj mus los tab sis muaj cov khoom muaj zog uas xav tau kev tswj cov khoom pov tseg kom raug.

1. Pravadoline tsis raug cais raws li cov nplaim hluav taws kub heev tab sis tuaj yeem decompose nyob rau hauv hluav taws kub, emitting fumes lom xws li carbon monoxide, carbon dioxide, thiab nitrogen oxides thaum thermal decomposition.
2. Siv cov tshuaj tsuag dej, cov hmoov qhuav qhuav, ua npuas dej, lossis cov pa roj carbon dioxide los tua hluav taws uas cuam tshuam nrog cov khoom.
3. Cov neeg tua hluav taws Pravadoline CAS 92623-83-1 yuav tsum hnav cov cuab yeej ua pa ntawm tus kheej thiab cov khaub ncaws tiv thaiv tag nrho thaum tuav cov kub hnyiab pravadoline vim muaj cov pa phem decomposition thiab tiv thaiv kev sib cuag ntawm daim tawv nqaij thiab qhov muag.
4. Thaum lub sij hawm combustion, tej zaum yuav emit irritant thiab toxic fumes; muaj cov hluav taws kub nyhiab los ntawm kev tswj hluav taws los yog cov dej dilution los tiv thaiv ib puag ncig thiab muaj kuab paug.