Pimobendan CAS 74150-27-9

1. Pimobendan feem ntau yog siv los ua cov tshuaj kho tsiaj (lub npe npe Vetmedin) rau kev tswj cov hlab plawv tsis ua haujlwm hauv cov dev vim dilated cardiomyopathy (DCM) lossis valvular insufficiency.
2. Pimobendan CAS 74150-27-9 ua haujlwm raws li kev xaiv inhibitor ntawm phosphodiesterase III (PDE3) nrog IC50 ntawm 0.32 µM, thaum tseem nthuav tawm cov khoom siv calcium-sensitizing uas txhim kho myocardial contractility yam tsis muaj qhov xav tau oxygen ntxiv.
3. Pimobendan yog ua hauj lwm nyob rau hauv kev tshawb fawb plawv raws li ib tug inodilator, muab ob qho tib si zoo inotropic los ntawm calcium sensitization ntawm plawv myofibrils thiab vasodilatory los ntawm PDE3 inhibition.
4. Cov kws tshawb fawb siv Pimobendan CAS 74150-27-9 hauv kev sim ua qauv ntawm lub plawv tsis ua hauj lwm, qhov kev tshawb fawb tau pom tias kev kho pimobendan hauv EMC tus kab mob ua rau mob myocarditis murine qauv tau txhim kho qhov kawg ciaj sia taus ntawm 33.6% (tswj) mus rau 53.3% / kg (0.) .

1. Pimobendan yuav tsum tau muab cia rau hauv lub thawv kaw nruj nreem nyob rau hauv qhov txias, qhuav, thiab zoo - qhov cua qhov chaw ntawm -20℃rau kev ruaj ntseg mus ntev (txog 3 xyoos hauv cov hmoov hmoov), los yog ntawm 2-8℃rau lub sij hawm luv.
2. Pimobendan CAS 74150-27-9 muaj cov tshuaj active tshuaj uas yuav tsum tau tuav nkaus xwb los ntawm cov neeg ua haujlwm cob qhia, raws li nws yog cais nrog cov lus txaus ntshai xws li R28 (muaj tshuaj lom heev yog nqos), R38 ( khaus khaus ntawm daim tawv nqaij), thiab R41 (kev pheej hmoo ntawm kev puas tsuaj loj rau qhov muag).
3. Cov neeg ua haujlwm yuav tsum hnav cov tshuaj lom neeg- cov hnab looj tes tiv thaiv roj hmab, NIOSH/MSHA- pom zoo ua pa ua pa, tsom iav tiv thaiv tshuaj lom neeg, thiab cov khaub ncaws tiv thaiv tsis zoo thaum tuav pimobendan, zam kev nqus cov plua plav thiab tiv thaiv daim tawv nqaij, qhov muag, thiab khaub ncaws.
4. Tsis txhob khaws cov tshuaj aqueous rau ntau tshaj ib hnub, thiab khaws cov khoom kom deb ntawm cov khoom siv tsis zoo xws li cov kua qaub / alkali, muaj zog oxidizing / txo cov neeg ua haujlwm, thiab tiv thaiv lub teeb thiab kub.

1. Cais qhov chaw nchuav, ua kom muaj cua txaus, thiab hnav cov khoom tiv thaiv tus kheej tag nrho nrog rau tus kheej -cov cuab yeej ua pa thiab cov khaub ncaws tiv thaiv thaum pimobendan raug tso tawm, tsis txhob muaj plua plav.
2. Sau Pimobendan CAS 74150-27-9 los ntawm kev cheb lossis nqus tsev yam tsis tsim cov plua plav, lossis nqus cov kev daws teeb meem nrog cov hmoov ua kua-binding khoom (diatomite, universal binders), thiab muab tso rau hauv cov thawv kaw tsim nyog rau kev pov tseg.
3. Decontaminate qhov chaw thiab cov khoom siv los ntawm kev txhuam nrog cawv, thiab tiv thaiv cov khoom los ntawm kev nkag mus rau hauv cov dej ntws los yog cov chav dej vim muaj kev phom sij ib puag ncig.
4. Tshem tawm cov khoom siv pov tseg raws li lub teb chaws, tseem fwv, xeev, thiab cov kev cai hauv cheeb tsam, vim tias cov khoom raug suav tias tsis yog - phom sij rau kev thauj mus los tab sis muaj cov khoom muaj zog.

1. Pimobendan tsis raug cais raws li cov nplaim hluav taws kub heev tab sis tuaj yeem decompose nyob rau hauv hluav taws kub, emitting fumes lom xws li carbon monoxide, carbon dioxide, thiab nitrogen oxides thaum thermal decomposition.
2. Siv Pimobendan CAS 74150-27-9 dej tshuaj tsuag, tshuaj qhuav hmoov, ua npuas ncauj, los yog carbon dioxide tua hluav taws uas muaj cov khoom.
3. Cov neeg tua hluav taws yuav tsum hnav tus kheej- muaj cov cuab yeej ua pa thiab cov khaub ncaws tiv thaiv tag nrho thaum tuav cov pimobendan kub hnyiab vim muaj cov pa phem decomposition thiab tiv thaiv kev sib cuag ntawm daim tawv nqaij thiab qhov muag.
4. Thaum lub sij hawm combustion, tej zaum yuav emit irritant fumes; muaj cov hluav taws kub hnyiab los tiv thaiv ib puag ncig, thiab txav cov thawv los ntawm qhov chaw tua hluav taws yog tias muaj kev nyab xeeb ua li ntawd.