5-Fluorouracil CAS 51-21-8

1. 5-Fluorouracil yog ib qho pyrimidine analog antimetabolite feem ntau siv los ua cov tshuaj tiv thaiv kab mob zoo rau kev kho mob qog noj ntshav ntawm lub mis, txoj hnyuv, qhov quav, plab, thiab mob qog noj ntshav.
2. 5-Fluorouracil CAS 51-21-8 ua haujlwm los ntawm inhibiting thymidylate synthase, uas depletes intracellular dTTP pas dej thiab cuam tshuam DNA synthesis; 5-Fluorouracil kuj tseem metabolized rau ribonucleotides thiab deoxyribonucleotides uas koom ua ke rau hauv RNA thiab DNA, inducing apoptosis.
3. 5-Fluorouracil yog ua hauj lwm hauv kev tshawb fawb daim ntawv thov suav nrog cov kev tshawb fawb ntawm pawg ntseeg, biofilm inhibition, thiab ua reagent rau inducing gastropathy (gastric mucosal raug mob) thiab xeev siab / ntuav hauv preclinical qauv .
4. Hauv kev tsim tshuaj, 5-Fluorouracil CAS 51-21-8 ua haujlwm ua niam txiv sib xyaw rau ntau cov tshuaj, suav nrog capecitabine, doxifluridine, tegafur, thiab S-1 (tegafur ua ke nrog gimeracil thiab potassium oxonate).

1. 5-Fluorouracil CAS 51-21-8 yuav tsum muab khaws cia rau hauv lub thawv kaw nruj nreem rau hauv qhov chaw txias, qhuav, thiab qhov cua zoo, tiv thaiv lub teeb, nrog kev pom zoo cia ntawm chav tsev kub hauv qhov txias, tsaus qhov chaw qis dua 15 degree.
2. 5-Fluorouracil ruaj khov mus txog 3 xyoos ntawm -20℃lossis 2 xyoos ntawm 4℃thaum khaws cia ua hmoov; Cov kev daws teeb meem yuav tsum tau muab khaws cia ntawm -20℃txog li 1 lub hlis lossis ntawm -80℃txog li 6 lub hlis, tsis txhob rov ua kom khov-thaw mus.
3. 5-Fluorouracil CAS 51-21-8 yog cais nrog GHS lub teeb liab lo lus "Danger" thiab cov nqe lus txaus ntshai H301 (Toxic yog nqos), H315 (Ua rau tawv nqaij khaus), thiab H319 (Ua rau qhov muag khaus hnyav); nws yog ib qho tshuaj txaus ntshai uas yuav tsum tau tuav tsuas yog los ntawm cov neeg ua haujlwm raug cob qhia.
4. Khaws 5-Fluorouracil kom deb ntawm cov ntaub ntawv tsis sib xws xws li cov oxidizing muaj zog thiab cov hauv paus muaj zog; nws muaj WGK Lub Tebchaws Yelemees 3 kev faib tawm (muaj peev xwm ua rau muaj dej txaus ntshai) thiab yuav tsum tsis txhob tso rau hauv ib puag ncig.

1. Tshem tawm ntawm qhov chaw nchuav, xyuas kom muaj qhov cua txaus, thiab hnav cov khoom tiv thaiv tus kheej nrog rau cov tshuaj -cov hnab looj tes tiv thaiv roj hmab, looj tsom iav, thiab NIOSH/MSHA- tso cai ua pa thaum 5-Fluorouracil tso tawm.
2. Sau 5-Fluorouracil CAS 51-21-8 los ntawm kev cheb lossis nqus tsev yam tsis tsim cov plua plav siv cov cuab yeej tsis ua kom tawg; rau cov kev daws teeb meem, nqus nrog cov ntaub ntawv inert xws li diatomite lossis universal binders.
3. Tsis txhob tsim cov huab cua thaum lub sij hawm ntxuav kom tsis txhob ua pa; decontaminate qhov chaw thiab khoom siv los ntawm kev txhuam nrog cawv, thiab tiv thaiv 5-Fluorouracil los ntawm kev nkag mus rau cov dej ntws los yog cov dej hauv chav dej.
4. Pov tseg cov ntaub ntawv khaws tseg raws li hauv zos, xeev, thiab tseem fwv cov kev cai ib puag ncig; 5-Fluorouracil raug cais raws li UN2811 (Toxic solid, organic, nos) nrog rau pawg III rau kev thauj mus los.

1. 5-Fluorouracil tsis raug cais raws li cov nplaim hluav taws kub heev tab sis yog cov khoom siv hluav taws xob uas tuaj yeem tawg tau nyob rau hauv qhov hluav taws kub, tawm cov pa phem xws li carbon monoxide, carbon dioxide, thiab nitrogen oxides (NOx).
2. Siv cov tshuaj tsuag dej, tshuaj qhuav hmoov, carbon dioxide, los yog cawv- ua npuas ncauj los tua hluav taws uas muaj 5-Fluorouracil; Tsis txhob siv lub dav hlau dej ncaj qha raws li 5-Fluorouracil CAS 51-21-8 tuaj yeem tawg cov khoom tawg.
3. Cov neeg tua hluav taws yuav tsum hnav nws tus kheej- muaj cov cuab yeej ua pa hauv siab- thov, MSHA/NIOSH tau pom zoo, thiab cov iav tiv thaiv tag nrho thaum tuav cov hluav taws kub 5-Fluorouracil vim muaj cov pa phem uas tsim los ntawm thermal decomposition .
4. Thaum lub sij hawm combustion, 5-Fluorouracil yuav emit irritant thiab toxic fumes; muaj cov hluav taws kub nyhiab los tiv thaiv ib puag ncig thiab tsis txhob tso rau hauv cov dej.