Tert -Butyldimethylsilyl Chloride CAS 18162-48-6

1. Tert-Butyldimethylsilyl chloride yog ntau yam organosilicon compound feem ntau siv los tiv thaiv reagent rau cawv, amines, amides, thiab ntau yam carboxylic acids hauv cov organic synthesis . Nws yog tus qauv reagent rau kev qhia txog TBDMS cov pab pawg tiv thaiv, uas yog qhov txaus siab rau nws txoj kev ruaj ntseg thiab kev xaiv hauv ntau - kauj ruam synthesis .
2.Tert-Butyldimethylsilyl chloride CAS 18162-48-6 feem ntau yog siv rau hauv kev sib txuas ntawm cov kws kho mob nyuaj, suav nrog prostaglandins, thiab ua cov khoom pabcuam rau hypolipemics xws li lovastatin thiab simvastatin . Nws kuj tseem ua lub luag haujlwm tseem ceeb hauv kev npaj ntawm isoxazolines N-oxides thiab hauv ribonucleoside synthesis.
3. Cov ntawv thov ntawm Tert-Butyldimethylsilyl chloride kuj suav nrog nws siv los ua tus neeg sawv cev derivatisation hauv cov ntawv thov roj chromatography/mass spectrometry (GC/MS), hauv kev npaj cov silicon-raws li cov ntaub ntawv rau kev hloov kho deg , thiab ua ib qho tseem ceeb anion trapping reagent .

1. Khaws Tert-Butyldimethylsilyl chloride nyob rau hauv ib lub thawv kaw nruj nreem nyob rau hauv ib tug inert roj (xws li, argon) nyob rau hauv ib tug txias, qhuav, thiab zoo- qhov cua qhov chaw, raws li nws yog noo noo rhiab heev thiab hydrolyzes nkag. Pom zoo cia kub sib txawv ntawm 0-8℃(txias) mus rau qhov txias, tsaus qhov chaw qis dua 15 degree.
2. Khaws Tert-Butyldimethylsilyl chloride nruj me ntsis kom deb ntawm cov muaj zog oxidizing cov neeg ua haujlwm, dej, cawv, amines, muaj zog acids, thiab cov hauv paus muaj zog, vim tias kev sib cuag yuav ua rau muaj kev puas tsuaj rau kev puas tsuaj thiab tso cov roj corrosive.
3. Ib txwm Tert-Butyldimethylsilyl chloride CAS 18162-48-6 siv cov cuab yeej tiv thaiv tus kheej tsim nyog (PPE) suav nrog cov tsom iav nruj nruj, npog ntsej muag, tshuaj lom neeg- hnab looj tes tiv thaiv (nitrile roj hmab, yam tsawg kawg nkaus 0.11 mm thickness), thiab cov khaub ncaws tiv thaiv nplaim taws. Kov tsuas yog ua kom muaj cua txaus los yog hauv cov fume hood, tsis txhob ua pa plua plav lossis vapors, thiab siv cov khoom tawg-pov thawj vim nws yog cov khoom tawg.

1. Tam sim ntawd cais qhov chaw nchuav, tshem tawm tag nrho cov khoom siv hluav taws xob, thiab xyuas kom muaj cua txaus. Siv cov cuab yeej tiv thaiv tus kheej tag nrho suav nrog tus kheej - muaj cov cuab yeej ua pa (SCBA). Tsis txhob cia Tert-Butyldimethylsilyl chloride nkag mus rau hauv cov dej los yog cov dej.
2. Muaj Tert-Butyldimethylsilyl chloride siv qhuav, inert, tsis yog- cov khoom siv hluav taws xob (xws li cov xuab zeb qhuav). Carefully sweep up or collect the material using an electrically protected vacuum cleaner or non-sparking tools, avoiding dust generation, and place it into a sealed, labeled corrosion-resistant chemical waste container for proper disposal according to hazardous material regulations .
3. Cov neeg ua haujlwm Tert-Butyldimethylsilyl chloride CAS 18162-48-6 yuav tsum hnav PPE tsim nyog thaum ntxuav. Dej hydrolyzes cov khoom, liberating acidic gas uas nyob rau hauv kev sib cuag nrog hlau nto tuaj yeem tsim flammable thiab / los yog explosive hydrogen gas. Tert-Butyldimethylsilyl chloride yog cais rau kev thauj mus los raws li UN2925 (Hazard Class 4.1/8, Packing Group II).

1. Tert-Butyldimethylsilyl chloride yog cais nrog GHS teeb liab lo lus "Danger". Nws yog ib qho khoom tawg yooj yim (H228) thiab corrosive, ua rau tawv nqaij kub hnyiab thiab qhov muag loj (H314 / H318). Nws raug xav tias yuav ua rau mob qog noj ntshav (H351) thiab ua rau muaj kev xeeb tub lossis tus menyuam hauv plab (H361), thiab tuaj yeem ua rau lub cev puas tsuaj los ntawm kev raug ncua ntev lossis rov ua dua (H373).
2. Tert-Butyldimethylsilyl chloride muaj qhov taw tes ntawm 22℃(72℃F), melting point range ntawm 86-89 degree, thiab kub taw tes ntawm 125℃. Nws yog noo noo rhiab heev thiab decomposes nyob rau hauv kev sib cuag nrog dej, tso tshuaj lom thiab corrosive hydrogen chloride gas. Thermal decomposition ua rau cov pa phem thiab khaus xws li carbon oxides, hydrogen chloride, thiab silicon oxides. Nws muaj teeb meem yog tias nqos tau (H302) thiab yuav ua rau tuag taus yog tias nqos thiab nkag mus rau hauv cov hlab ntsws (H304).
3. Ib txwm Tert-Butyldimethylsilyl chloride CAS 18162-48-6 sab laj rau Daim Ntawv Qhia Kev Nyab Xeeb tshwj xeeb (SDS) rau Tert-Butyldimethylsilyl chloride kom tiav cov ntaub ntawv txaus ntshai, cov txheej txheem pab thawj zaug (P303+P3}, P3} P305+P351+P338+P310 rau qhov muag, P304+P340+P310 rau kev nqus pa, P301+P330+P331 rau kev noj - tsis txhob ntuav ntuav), thiab cov lus qhia tuav. Cov lus ceeb toom muaj xws li P210 (kom deb ntawm tshav kub / taws / qhib nplaim taws), P233 (kom kaw lub thawv kom nruj), P260 (tsis txhob ua pa plua plav), thiab P280 (hnav looj hnab looj tes / tiv thaiv qhov muag).